Projects

Survivorship Epidemiology:

The goal of this program of methodological research is to advance theory, concepts, models, and tools for descriptive, predictive, and inferences about critical illness survivor health outcomes, their pathology and diagnosis, biomedical treatment, the physiological and psychological changes associated with these processes, and their sociocultural contexts, including financial and economic burdens, healthcare services, and advances in pharmaceutical treatment , aprocesses, services relevant to them.

I am creating an international network of epidemiologists studying critical illness survivorship. The object of this network is the establishment of an academic society dedicated to advancing dialogue, theory, methods, and applications to improve the rigor, representativeness, relevance, and reproducibility of the epidemiological study of critical illness survivorship.

Specific Aims

  1. Distilling epidemiological principles common to survivorship and forming them into coherent quantitative theory,

  2. Developing epidemiological methods to analyze survivor health outcomes selecting relevant com- parator groups, and coupling them with estimators that can reasonably be assumed to estimate quantities of interest in survivorship research;

  3. Define the limits of generalizability for estimands and estimators within and across fields of medicine, patient populations, and geographies.

Publications

  1. Basham CA, Romanowski K, Johnston JC. Life after tuberculosis: planning for health. Lancet Respiratory Medicine. 2019;7(12):1004–1006.

  2. Basham CA. Post–tuberculosis outcomes science: a sub–discipline for TB survivorship research? International Journal of Tuberculosis and Lung Disease. 2021; 25(6):498-501.

  3. Basham CA, Smith S, Romanowski K, Johnston JC. Cardiovascular morbidity and mortality among people diagnosed with tuberculosis: a systematic review and meta-analysis. PLoS ONE 15(7):e0235821.

  4. Basham CA, Cook, VJ, Johnston JC. Towards a ‘fourth 90’: A population–based analysis of post–tuberculosis pulmonary function testing in British Columbia, Canada, 1985–2015. European Respiratory Journal. April 2020:2000384.

  5. Basham CA, Karim ME, Cook VJ, Patrick DM, Johnston JC. Post–tuberculosis mortality risk among immigrants to British Columbia, Canada, 1985–2015: a time–dependent Cox regression analysis of linked immigration, public health, and vital statistics data. Can J Public Heal. 2021;112(1):132–141.

  6. Basham CA, Karim ME, Cook, VJ, Patrick DM, Johnston JC. Post–tuberculosis airway disease among people immigrating to British Columbia, Canada, 1985–2015: a population–based cohort study. EClinicalMedicine. 2021;33:100752.

  7. Basham CA, Karim ME, Cook, VJ, Patrick DM, Johnston JC. Tuberculosis–associated depression risk: a population–based cohort study of people immigrating to British Columbia, Canada, 1985–2015. Annals of Epidemiology. 2021; 63: 7-14.

  8. Basham CA, Karim ME. An E–value analysis of potential unmeasured or residual confounding in systematic reviews of post–TB mortality, respiratory disease, and cardiovascular disease. Annals of Epidemiology. 2022; 68: 24-31.

  9. Basham CA, Karim ME, Johnston JC. Multimorbidity prevalence and chronic disease patterns among tuberculosis survivors in a high-income setting. Can J Public Heal. 2023 Apr;114(2):264-276.